| Back to Back Issues Page |
 |
|
HeadWay Issue #241 - When other meds don't work - Rimegepant for Migraine? March 17, 2026 |
| Hi! In this issue: Finally - a Newsletter!Rimegepant for Migraine (when other meds don't work)Finally - a Newsletter!And - a personal note! :)As I mentioned recently at Headache and Migraine News, this past year has been one of the most challenging years of my life. As a result, I've been communicating very little with you - but I hope that will improve in the future. World news and even health news has, in my opinion, been drowning out migraine research and advocacy, something that is still very much needed. Headache news is not the only news of importance in the world - but for someone unable to function because of a headache, it remains a top priority. It's important to mention that many people are continuing on with the fight, and that includes the people at the Migraine World Summit. You can still catch two more days of the summit (today and tomorrow), which features very up to date information about migraine and headaches. If you hop on now, you can catch interviews with experts on topics such as:
You also have until tomorrow to get the full library of interviews plus a lot of updated treatment information for a discount. Check out what the library includes here. Rimegepant for Migraine (when other meds don't work)One important news item that continues to develop is the research being done on CGRP related medications. Rimegepant is one of these which is getting a lot of attention.Rimegepant is a a CGRP receptor antagonist, a type of drug that early on was recognized for its quick action during a migraine attack. But back in 2021 Nurtec ODT (a brand name for the drug) was also approved as a preventative. Since then, rimegepant is getting attention as a medication that may have a wide benefit for migraine patients, both to stop an attack in its tracks, and to stop an attack before it starts. Two Phase 4 studies have shown good results for rimegepant. One was focused on patients with episodic (not chronic) migraine who had not had much success with several other categories of medications, finding that they tended to have fewer days with migraine with rimegepant. This has been a constant hope with new meds, that they will help those who have not been helped by earlier drugs. More on this trial: "... efficacy and tolerability of rimegepant for the prevention of episodic migraine in adults with a history of inadequate response to traditional oral preventive medications". A second trial focused on those who were not taking triptans (well-known migraine targetting drugs) because a) they didn't work or b) they couldn't tolerate them or c) they were encouraged to avoid them for medical reasons. At the 2 hour mark more than half these patients had significant improvement (that's what the study marked as a time frame - that's not to say that there was no improvement earlier!). Read more here: "Rimegepant for acute treatment of migraine in triptan-unsuitable adults". This is just a small slice of news, but if you haven't considered medications such as rimegepant because you've had so many disappointments with other meds, maybe it's time to talk to your doctor about options that may work for you. Thanks for reading! Remember, if you have feedback or ideas for future issues, visit the HeadWay MailRoom. Your password is nomoache. |
| Back to Back Issues Page |